Dicer (DICER1) Mouse Monoclonal Antibody [Clone ID: S167-7]
CNY 5,830.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
Product Data | |
Clone Name | S167-7 |
Recommend Dilution | WB: 1ug/ml |
Reactivity | Mouse, Rat, Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer |
Formulation | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
Concentration | lot specific |
Purification | Protein G Purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | dicer 1, ribonuclease III |
Database Link | |
Background | Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) . After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha , pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs . The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA . |
Synonyms | DCR1; Dicer; Dicer1e; HERNA; K12H4.8-LIKE; MNG1; RMSE2 |
Note | Detects ~215kDa. |
Reference Data | |
Protein Families | Druggable Genome |
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