Gria2 Mouse Monoclonal Antibody [Clone ID: S21-32]

Specifications

Product Data
Clone Name	S21-32
Applications	IHC, WB
Recommend Dilution	WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 834-883 (cytoplasmic C-terminus) of rat GluR2
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	glutamate ionotropic receptor AMPA type subunit 2
Database Link	NP_058957 Entrez Gene 2891 HumanEntrez Gene 14800 MouseEntrez Gene 29627 Rat UniProt ID P19491
Background	The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers . GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium .
Synonyms	GluA2; gluR-B; GluR-K2; GLUR2; GluR2; GLURB; HBGR2
Note	Detects ~90kDa.
Reference Data

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