Kcnb1 Mouse Monoclonal Antibody [Clone ID: S89-34]

Specifications

Product Data
Clone Name	S89-34
Applications	IHC, WB
Recommend Dilution	WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide amino acids 837-853 (cytoplamsic C-terminus) of rat KV2.1 (HMLPGGGAHGSTRDQSI)
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	potassium voltage-gated channel subfamily B member 1
Database Link	NP_037318 Entrez Gene 3745 HumanEntrez Gene 16500 MouseEntrez Gene 25736 Rat UniProt ID P15387
Background	Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia .
Synonyms	DRK1; h-DRK1; Kv2.1
Note	Detects ~105-125kDa (varies with cell background due to phosphorylation). No cross reactivity to rat Kv2.2.
Reference Data

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