Mmp9 Mouse Monoclonal Antibody [Clone ID: S51-82]

Specifications

Product Data
Clone Name	S51-82
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 1-708 (full length) of rat MMP9
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	matrix metallopeptidase 9
Database Link	NP_112317 Entrez Gene 4318 HumanEntrez Gene 17395 MouseEntrez Gene 81687 Rat UniProt ID P50282
Background	MMP9, otherwise known as matrix metalloproteinase 9, is involved in the breakdown of extracellular matrix innormal physiological processes such as embryonic development, reproduction and tissue remodeling, aswell as in disease processes like arthritis and metastasis .Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis . MMP activity correlates with cancer development . One mechanism of MMP regulation is transcriptional . Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein .
Synonyms	CLG4B; GELB; MANDP2; MMP-9
Note	Detecs ~92kDa and ~82kDa (pro and active forms)
Reference Data

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