IL9 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	IL-9 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-9.
Formulation	IL-9 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	IL-9 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 13 kDa; Observed: 22 kDa
Gene Name	interleukin 9
Database Link	NP_000581 Entrez Gene 3578 Human UniProt ID P15248
Background	Interleukin 9 (IL-9) is a cytokine secreted by TH2 lymphocytes that acts as a regulator of a variety of hematopoietic cells, stimulates cell proliferation and prevents apoptosis (1,2). It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins (3). The IL-9 gene has been identified as a candidate gene for asthma (4). Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness (5).
Synonyms	HP40; IL-9; P40
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Asthma, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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