APPBP2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	APPBP2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APPBP2.
Formulation	APPBP2 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	APPBP2 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 64 kDa; Observed: 57 kDa
Gene Name	amyloid beta precursor protein binding protein 2
Database Link	NP_006371 Entrez Gene 66884 MouseEntrez Gene 303396 RatEntrez Gene 10513 Human UniProt ID Q92624
Background	The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1). The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2). APPBP2 has been found to be highly expressed in breast cancer (3).
Synonyms	APP-BP2; HS.84084; PAT1
Reference Data
Protein Families	Druggable Genome

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