AMIGO1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	AMIGO1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AMIGO1
Formulation	AMIGO1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	AMIGO1 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 54 kDa; Observed: 55 kDa
Gene Name	adhesion molecule with Ig-like domain 1
Database Link	NP_065754 Entrez Gene 229715 MouseEntrez Gene 295365 RatEntrez Gene 57463 Human UniProt ID Q86WK6
Background	The amphoterin-induced gene and ORF (AMIGO1) protein is a brain-enriched, glycosylated transmembrane immunoglobulin (Ig) superfamily protein with six extracellular leucine-rich repeats (LRRs) and one Ig-like domain. It and the related proteins AMIGO2 and AMIGO3 are thought to be cell adhesion molecules expressed on fiber tracts of neuronal tissues and participate in their formation (1). AMIGO1 has also been suggested to play important roles in dendritic outgrowth during development and could modulate the survival of developing and adult neurons (2).
Synonyms	ALI2; AMIGO; AMIGO-1
Reference Data
Protein Families	Transmembrane

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