LC3B (MAP1LC3B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	MAP1LC3B antibody was raised against an 18 amino acid peptide near the amino terminus of human MAP1LC3B.
Formulation	MAP1LC3B antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	MAP1LC3B antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 14 kDa; Observed: 14 kDa
Gene Name	microtubule associated protein 1 light chain 3 beta
Database Link	NP_073729 Entrez Gene 64862 RatEntrez Gene 67443 MouseEntrez Gene 81631 Human UniProt ID Q9GZQ8
Background	Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3B belongs to the MAP1 LC3 family and it includes 3 different light chains, LC1, LC2 and LC3 (2). MAP1LC3B is involved in formation of autophagosomal vacuoles (autophagosomes) (3). It is most abundant in heart, brain, skeletal muscle and testis. MAP1LC3B is essential for autophagy and associated to the autophagosome membranes after processing (4).
Synonyms	1BLC3; ATG8F; LC3B; MAP1A; MAP1LC3B-a
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.