C19orf80 (ANGPTL8) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Betatrophin antibody was raised against a 16 amino acid peptide near the amino terminus of human Betatrophin. The immunogen is located within amino acids 40 - 90 of Betatrophin.
Formulation	Betatrophin antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Betatrophin antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 22 kDa; Observed: 22 kDa
Gene Name	angiopoietin like 8
Database Link	NP_061157 Entrez Gene 624219 MouseEntrez Gene 100361444 RatEntrez Gene 55908 Human UniProt ID Q6UXH0
Background	The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3).
Synonyms	C19orf80; PRO1185; PVPA599; RIFL; TD26
Reference Data

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