ARF6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	ARF6 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ARF6.
Formulation	ARF6 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	ARF6 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 19 kDa; Observed: 18 kDa
Gene Name	ADP ribosylation factor 6
Database Link	NP_001654 Entrez Gene 11845 MouseEntrez Gene 79121 RatEntrez Gene 382 Human UniProt ID P62330
Background	The ADP-ribosylation factor 6 (ARF6) is a member of the ARF family, which is part of the RAS superfamily (1). The ARF proteins are small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D (2). The product of this gene is localized to the plasma membrane (3), and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling (4).
Synonyms	DKFZp564M0264
Reference Data
Protein Pathways	Endocytosis, Fc gamma R-mediated phagocytosis

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