Lin28 (LIN28A) Mouse Monoclonal Antibody [Clone ID: 1G9H9]

Specifications

Product Data
Clone Name	1G9H9
Applications	WB
Recommend Dilution	WB: 0.5 - 1 ug/mL
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Mouse monoclonal Lin28 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Lin28.
Formulation	Lin28 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Lin28 Monoclonal Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 23 kDa
Gene Name	lin-28 homolog A
Database Link	NP_078950 Entrez Gene 79727 Human UniProt ID Q9H9Z2
Background	Lin28 Monoclonal Antibody: Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
Synonyms	CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1
Reference Data
Protein Families	Transcription Factors

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