Hsp60 (HSPD1) Rabbit Polyclonal Antibody
CAT#: TA326868
Rabbit anti-HSPD1 Polyclonal Antibody
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Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:500 - 1:2000;IHC 1:50 - 1:200 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human HSPD1 |
Formulation | Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 61 kDa |
Gene Name | heat shock protein family D (Hsp60) member 1 |
Database Link | |
Background | In both prokaryotic and eukaryotic cells the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones. HSP60 has primarily been known as a mitochondrial protein that is important for folding key proteins after import into the mitochondria. It is now clear that a significant amount of HSP60 is also present in the cytosol of many cells and that it is induced by stress, inflammatory and immune responses, autoantibodies correlated with Alzheimers, coronary artery diseases, MS, and diabetes. |
Synonyms | CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13 |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | RNA degradation, Type I diabetes mellitus |
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