PD-L1 (CD274) Rabbit Polyclonal Antibody
CAT#: TA327120
CD274 Rabbit Polyclonal Antibody
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CNY 1,999.00
CNY 2,700.00
货期*
2周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Applications | ICC/IF, IHC, WB |
Recommend Dilution | WB 1:500 - 1:2000;IF 1:20- 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human CD274 |
Formulation | PBS with 0.05% proclin300,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 33 kDa |
Gene Name | CD274 molecule |
Database Link | |
Background | Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens. It also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. |
Synonyms | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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The co-expression characteristics of LAG3 and PD-1 on the T cells of patients with breast cancer reveal a new therapeutic strategy
,Du, H;Yi, Z;Wang, L;Li, Z;Niu, B;Ren, G;,
Int. Immunopharmacol.
,PubMed ID 31841754
[CD274]
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