LXR alpha (NR1H3) Rabbit Polyclonal Antibody

CAT#: TA327294

Rabbit anti-NR1H3 Polyclonal Antibody



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货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500-1:2000
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human NR1H3
Formulation PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name nuclear receptor subfamily 1 group H member 3
Background The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms LXR-a; LXRA; RLD-1
Reference Data
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways PPAR signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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