PPP2R2A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB 1:500 - 1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human PPP2R2A
Formulation	Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	protein phosphatase 2 regulatory subunit Balpha
Database Link	NP_002708 Entrez Gene 71978 MouseEntrez Gene 117104 RatEntrez Gene 5520 Human UniProt ID P63151
Background	Protein phosphatase 2A subunit B isoform R2-a (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B. Evidence suggests that subunit PPP2R2A enhances TGF-β, Activin, and Nodal signaling pathways and may play an important role in cell cycle regulation. PPP2R2A/PP2A, B55-a/PR55-a isoform interacts with the type I TGF-β receptors via unique WD-40 repeats that contribute to the anti-proliferative function of TGF-β receptors.
Synonyms	B55A; B55ALPHA; PR52A; PR55A
Reference Data
Protein Families	Druggable Genome, Phosphatase
Protein Pathways	Tight junction

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