H3FT (HIST3H3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, WB
Recommend Dilution	WB 1:500 - 1:2000;IF 1:20 - 1:50
Reactivity	Human, Mouse, Rat, Other (Wide Range)
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic methylated peptide corresponding to residues surrounding K14 of human histone H3
Formulation	Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	15 kDa
Gene Name	histone cluster 3, H3
Database Link	NP_003484 Entrez Gene 691496 RatEntrez Gene 8290 Human UniProt ID Q16695
Background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Synonyms	g; H3; H3.4; H3FT; H3t
Reference Data
Protein Pathways	Systemic lupus erythematosus

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