alpha smooth muscle Actin (ACTA2) Mouse Monoclonal Antibody [Clone ID: 1A4]

Specifications

Product Data
Clone Name	1A4
Applications	IHC
Recommend Dilution	IHC: 1:100 - 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	actin, alpha 2, smooth muscle, aorta
Database Link	NP_001604 Entrez Gene 59 Human UniProt ID P62736
Synonyms	AAT6; ACTSA; MYMY5
Note	Actin is a major component of the cytoskeleton and is present in most cell types. Anti-smooth muscle actin does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin is positive. Leiomyosarcomas are positive with both anti-muscle specific actin and anti-smooth muscle actin.
Reference Data
Protein Pathways	Vascular smooth muscle contraction

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