Cytokeratin 5 (KRT5) Rabbit Monoclonal Antibody [Clone ID: EP1601Y]
CAT#: TA327666
Rabbit Monoclonal Cytokeratin 5 Antibody
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CNY 9,413.00
货期*
5周
规格
经常一起买 (2)
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Specifications
Product Data | |
Clone Name | EP1601Y |
Applications | IHC |
Recommend Dilution | IHC: 1:50 - 1:200 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Formulation | This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | keratin 5 |
Database Link | |
Synonyms | CK5; DDD; DDD1; EBS2; K5; KRT5A |
Note | Cytokeratin 5 is an intermediate filament protein of 58 kD molecular weight within the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.Anti-cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Epithelioid mesotheliomas are strongly positive in all cases, but up to 11% of pulmonary adenocarinomas will show focal immunostaining. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas immunostain with anti-CK 5. Anti-CK 5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-CK 5. This antibody, along with anti-CK 14, has found application in identifying basal-like breast carcinoma, a tumor with poor prognosis. Some carcinomas of ovarian origin may display anti-CK 5 positivity. |
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