H3FT (HIST3H3) Rat Monoclonal Antibody [Clone ID: HTA28]

CAT#: TA327973

Rat Monoclonal anti-Histone H3 Phospho (Ser28) Antibody



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CNY 7,406.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Clone Name HTA28
Applications IF, WB
Recommend Dilution WB, IP, ICFC, IF, CyTOF
Reactivity Human
Host Rat
Clonality Monoclonal
Immunogen Synthetic peptide conjugated to KLH, corresponding to amino acids 23-35 of Human Histone H3.
Formulation This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
Concentration lot specific
Purification The antibody was purified by affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name histone cluster 3, H3
Background H3 is a core component of the nucleosome that serves to wrap and compact DNA into chromatin.Histones therefore, limit the accessibility of DNA, providing mechanisms for transcription regulation, DNA repair and replication and chromosomal stability.During mitosis, H3 is phosphorylated at serine 28.This phosphorylation coincides with chromosome condensation initiated at prophase and disappears at late anaphase H3 has been demonstrated to be phosphorylated by the action of MLTK-α (mixed linage kinase-like mitogen activated protein triple kinase α) in response to ultraviolet B light and epidermal growth factor, as well as Aurora-B during mitosis.
Synonyms g; H3; H3.4; H3FT; H3t
Reference Data
Protein Pathways Systemic lupus erythematosus
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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