ALIX (PDCD6IP) Mouse Monoclonal Antibody [Clone ID: 3A9]

CAT#: TA328026

Mouse Monoclonal anti-Alix Antibody



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CNY 4,257.00


货期*
5周

规格
    • 100 ug

Product images

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Specifications

Product Data
Clone Name 3A9
Applications WB
Recommend Dilution WB, IP, IF
Reactivity Human, Mouse, Frog
Host Mouse
Clonality Monoclonal
Immunogen Recombinant full-length human Alix protein
Formulation This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration lot specific
Purification The antibody was purified by affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 96 kD
Gene Name programmed cell death 6 interacting protein
Background Alix (ALG-2-interacting protein X) is an adaptor protein that was first described for its capacity to bind to the calcium-binding protein ALG-2, the expression of which seemed necessary for cell death. Predicted molecular weight approximately 96 kD. Alix contains an N-terminal Bro1 domain and a C-terminal proline-rich domain (PRD). The PRD contains multiple polyproline motifs, which are potential docking sites for proteins containing SH3 domains, interactwith multiple cellular Alix-binding partners that are involvedin apoptotic induction, endosomal sorting,and endocytosis. Bro1 domain interacts with CHMP4b which is also involved in endosomal sorting.
Synonyms AIP1; ALIX; DRIP4; HP95
Reference Data
Protein Families Druggable Genome
Protein Pathways Endocytosis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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