Macro H2A.2 (H2AFY2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This H2AFY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-169 amino acids from the Central region of human H2AFY2.
Formulation	PBS with 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	H2A histone family member Y2
Database Link	NP_061119 Entrez Gene 55506 Human UniProt ID Q9P0M6
Background	Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Synonyms	macroH2A2
Reference Data
Protein Pathways	Systemic lupus erythematosus

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.