Cckar Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	This Mouse Cckar antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the C-terminal region of mouse Cckar.
Formulation	PBS with 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	cholecystokinin A receptor
Database Link	NP_033957 Entrez Gene 24889 RatEntrez Gene 12425 Mouse UniProt ID O08786
Background	Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Synonyms	CCK-A; CCK-AR; CCK1-R; CCKRA
Reference Data

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