Cacna1g Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:200-1:2000; IHC: 1:100-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide MDEEEDGAGAEESGQPRSFTQL(C), corresponding to amino acid residues 1-22 of rat CaV3.1 (Accession O54898). Intracellular, N-terminus.
Formulation	Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Reconstitution Method	Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification	Affinity purified on immobilized antigen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	calcium voltage-gated channel subunit alpha1 G
Database Link	NP_113789 Entrez Gene 8913 HumanEntrez Gene 12291 MouseEntrez Gene 29717 Rat
Background	Voltage-dependent Ca2+ channels provide a pathway for rapid influx of Ca2+ into cells, which plays a crucial role in both electrical and metabolic signaling. T-type currents are transduced via channel proteins encoded by three genes that compose a subfamily within the Cav channel family. The activity of T-type channels contributes to several known physiological and pathophysiological phenomena including burst firing in neurons, pace making activity in the heart and secretion from endocrine tissues. There are three cloned T-type channel isoforms.CaV3.1 (a1G) and CaV3.2 (a1H) are widely distributed whereas the expression of CaV3.3 (a1I) is restricted to the central nervous system. CaV3.1 and CaV3.2 are also expressed in the kidney, but little is known about their physiological role there.
Synonyms	Ca(V)T.1; Cav3.1; MGC117234; NBR13
Reference Data

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