TRF1 (TERF1) Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 0.3-1ug/ml, ELISA: 1:32,000
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Internal region (NLDTRKSVSDKQS)
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	telomeric repeat binding factor 1
Database Link	NP_003209 Entrez Gene 7013 Human UniProt ID P54274
Background	TRF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus (1).
Synonyms	hTRF1-AS; PIN2; t-TRF1; TRBF1; TRF; TRF1
Reference Data
Protein Families	Transcription Factors

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