CD47 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, PEP-ELISA
Recommend Dilution	WB: 0.3-1ug/ml
Reactivity	Human, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	Internal region (near C terminus) (SNQKTIQPPRK)
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CD47 molecule
Database Link	NP_001768 Entrez Gene 478552 DogEntrez Gene 961 Human UniProt ID Q08722
Background	This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Synonyms	IAP; MER6; OA3
Note	This antibody is expected to recognize both reported isoforms (NP_001768.1; NP_942088.1).
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ECM-receptor interaction

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