Kappa Opioid Receptor (OPRK1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-OPRK1 antibody: synthetic peptide directed towards the N terminal of human OPRK1. Synthetic peptide located within the following region: DSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEP
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	43 kDa
Gene Name	opioid receptor kappa 1
Database Link	NP_000903 Entrez Gene 4986 Human UniProt ID P41145
Background	OPRK1 is a multi-pass membrane protein. It belongs to the G-protein coupled receptor 1 family. OPRK1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for dynorphins. OPRK1 may play a role in arousal and regulation of autonomic and neuroendocrine functions.
Synonyms	K-OR-1; KOR; KOR-1; OPRK
Note	Immunogen sequence homology: Human: 100%; Guinea pig: 91%; Pig: 85%; Mouse: 84%
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

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