IKB zeta (NFKBIZ) Rabbit Polyclonal Antibody
CNY 4,897.00
Cited in 1 publication. |
CNY 4,840.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western Blot: 1-3 ug/ml |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptides corresponding to an amino acid range between 270-320 and 670-720 of mouse IkB zeta protein were used as the immunogen for this antibody. |
Formulation | PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Protein G purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | NFKB inhibitor zeta |
Database Link | |
Background | IkappaBzeta (also known as MAIL and INAP) is an ankyrin-repeat-containing nuclear protein that is highly homologous to the IkappaB family member Bcl-3. Transcription of IkappaBzeta is upregulated by stimulation with TLR ligands, IL-1 and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells. IkappaB-zeta preferentially associates with the NF-kappaB subunit p50 rather than p65 and recombinant IkappaB-zeta proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer. |
Synonyms | IKBZ; INAP; MAIL |
Reference Data | |
Protein Families | Druggable Genome |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma
,Arthur, SE;Jiang, A;Grande, BM;Alcaide, M;Cojocaru, R;Rushton, CK;Mottok, A;Hilton, LK;Lat, PK;Zhao, EY;Culibrk, L;Ennishi, D;Jessa, S;Chong, L;Thomas, N;Pararajalingam, P;Meissner, B;Boyle, M;Davidson, J;Bushell, KR;Lai, D;Farinha, P;Slack, GW;Morin, GB;Shah, S;Sen, D;Jones, SJM;Mungall, AJ;Gascoyne, RD;Audas, TE;Unrau, P;Marra, MA;Connors, JM;Steidl, C;Scott, DW;Morin, RD;,
Nat Commun
,PubMed ID 30275490
[NFKBIZ]
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