Caspase 8 (CASP8) Mouse Monoclonal Antibody [Clone ID: 90A992]

CAT#: TA336388

Mouse Monoclonal Caspase-8 Antibody (90A992)



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CNY 5,381.00


货期*
5周

规格
    • 100 ug

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Transient overexpression lysate of caspase 8, apoptosis-related cysteine peptidase (CASP8), transcript variant A
    • 100 ug

CNY 4,840.00


Transient overexpression lysate of caspase 8, apoptosis-related cysteine peptidase (CASP8), transcript variant B
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Clone Name 90A992
Applications CyTOF-ready, FC, IHC, Simple Western, WB
Recommend Dilution Simple Western: 1:100, Immunohistochemistry-Paraffin: 4 ug/ml, Flow Cytometry: 0.1-0.5 ug/ml, Western Blot: 0.5-2 ug/ml, Immunohistochemistry, CyTOF-ready
Reactivity Human, Primate
Host Mouse
Clonality Monoclonal
Immunogen Amino acids PVETDSEEQP of human Caspase-8 were used as the immunogen for this antibody.
Formulation PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name caspase 8
Background Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme. Caspase-8 (FLICE) forms a direct link between the activation of CD95 and the caspase pathway. Overexpression of Caspase-8 induces apoptosis, which can be blocked by inhibitors specific for the ICE family.
Synonyms ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Alzheimer's disease, Apoptosis, Huntington's disease, NOD-like receptor signaling pathway, p53 signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Viral myocarditis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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