Dnmt2 (TRDMT1) Mouse Monoclonal Antibody [Clone ID: 102B1259.2]

Specifications

Product Data
Clone Name	102B1259.2
Applications	FC, WB
Recommend Dilution	Western Blot: 1:100-1:2000, Flow Cytometry: 1-5 ug/ml
Reactivity	Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	This antibody was raised against synthetic peptides corresponding to mouse Dnmt2.
Formulation	PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	tRNA aspartic acid methyltransferase 1
Database Link	NP_004403 Entrez Gene 13434 Mouse UniProt ID O14717
Background	Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases.
Synonyms	DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cysteine and methionine metabolism, Metabolic pathways

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