VCAM1 Mouse Monoclonal Antibody [Clone ID: 6G9]

Specifications

Product Data
Clone Name	6G9
Applications	ELISA, IHC, Immunoblotting, IP, Simple Western, WB
Recommend Dilution	Simple Western: 1:1000, ELISA: 1:10000, Immunoprecipitation, Immunoblotting, Western Blot: 1:500-1:2000, Immunohistochemistry: 1:200-1:1000, Immunohistochemistry-Paraffin: 1:200-1:1000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human VCAM1 expressed in E. coli. [UniProt# P19320]
Formulation	PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Ammonium sulfate precipitation
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	81 kDa
Gene Name	vascular cell adhesion molecule 1
Database Link	NP_001069 Entrez Gene 7412 Human UniProt ID P19320
Background	VCAM1 is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.
Synonyms	CD106; INCAM-100
Note	This VCAM1 (6G9) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections and ELISA.
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

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