ASAH3 (ACER1) Rabbit Polyclonal Antibody
CAT#: TA343069
Rabbit Polyclonal Anti-ACER1 Antibody
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CNY 5,250.00
Cited in 1 publication. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-ACER1 antibody: synthetic peptide directed towards the C terminal of human ACER1. Synthetic peptide located within the following region: VNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVALTSWISD |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 31 kDa |
Gene Name | alkaline ceramidase 1 |
Database Link | |
Background | ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids. |
Synonyms | ALKCDase1; ASAH3 |
Note | Immunogen Sequence Homology: Human: 100%; Dog: 92%; Rabbit: 86%; Pig: 85%; Bovine: 79%; Rat; Guinea pig: 75% |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Inhibition of sphingosine 1phosphate lyase activates human keratinocyte differentiation and attenuates psoriasis in mice
,Jeon, S;Song, J;Lee, D;Kim, GT;Park, SH;Shin, DY;Shin, KO;Park, K;Shim, SM;Park, TS;,
J. Lipid Res.
,PubMed ID 31690639
[ACER1]
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