Cystatin C (CST3) Mouse Monoclonal Antibody [Clone ID: 7F6-A5-F3]

Specifications

Product Data
Clone Name	7F6-A5-F3
Applications	ELISA
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for CYC antibody: Recombinant human cystatin c protein.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	13 kDa
Gene Name	cystatin C
Database Link	NP_000090 Entrez Gene 1471 Human UniProt ID P01034
Background	Cystatin C or cystatin 3 (formerly gamma trace,post-gamma-globulin or neuroendocrine basic polypeptide),[2] a protein encoded by the CST3 gene,is mainly used as a biomarker of kidney function.Recently,it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease.It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition),such as Alzheimer's disease.In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids.It is found in virtually all tissues and body fluids.It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes).Cystatin C belongs to the type 2 cystatin gene family.
Synonyms	ARMD11; HEL-S-2
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

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