DDX3 (DDX3X) Mouse Monoclonal Antibody [Clone ID: 6G8-F4-E3]

Specifications

Product Data
Clone Name	6G8-F4-E3
Applications	IF, IP, WB
Recommend Dilution	WB: 1:1000, IF: 1:200
Reactivity	Human, Monkey, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for DDX3X antibody: purified recombinant human DDX3 protein fragments expressed in E.coli.
Formulation	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	75 kDa
Gene Name	DEAD-box helicase 3, X-linked
Database Link	NP_001347 Entrez Gene 13205 MouseEntrez Gene 317335 RatEntrez Gene 1654 Human UniProt ID O00571
Background	DEAD box proteins,characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD),are putative RNA helicases.They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation,nuclear and mitochondrial splicing,and ribosome and spliceosome assembly.Based on their distribution patterns,some members of this family are believed to be involved in embryogenesis,spermatogenesis,and cellular growth and division.This gene encodes a DEAD box protein,which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location.This gene has a homolog located in the nonrecombining region of the Y chromosome.The protein sequence is 91% identical between this gene and the Y-linked homolog.Alternative splicing results in multiple transcript variants. [provided by RefSeq,Jul 2010]
Synonyms	CAP-Rf; DBX; DDX3; DDX14; HLP2
Reference Data
Protein Families	ES Cell Differentiation/IPS
Protein Pathways	RIG-I-like receptor signaling pathway

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