Nucleophosmin (NPM1) Mouse Monoclonal Antibody [Clone ID: 2D9-C3-E5]

Specifications

Product Data
Clone Name	2D9-C3-E5
Applications	WB
Recommend Dilution	WB: 1:1000, IF: 1:200
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for NPM1 antibody: purified recombinant full length of human NPM1 protein expressed in E.coli.
Formulation	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	38 kDa
Gene Name	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Database Link	NP_002511 Entrez Gene 18148 MouseEntrez Gene 4869 Human UniProt ID P06748
Background	This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Synonyms	B23; NPM
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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