SHP1 (PTPN6) Mouse Monoclonal Antibody [Clone ID: 2B7-H7-F8]

CAT#: TA347034

Mouse Monoclonal SHP-1 Antibody

Size: 20 ul 100 ul



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CNY 2,700.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Clone Name 2B7-H7-F8
Applications WB
Recommend Dilution WB: 1:1000
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen The immunogen for PTPN6 antibody: purified recombinant human SHP-1 protein fragments expressed in E.coli.
Formulation Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Purification Affinity purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name protein tyrosine phosphatase, non-receptor type 6
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.
Synonyms HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; SHP1
Reference Data
Protein Families Druggable Genome, Phosphatase, Stem cell - Pluripotency
Protein Pathways Adherens junction, B cell receptor signaling pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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