TXNRD2 Mouse Monoclonal Antibody [Clone ID: 3F2-E12-F10]

Specifications

Product Data
Clone Name	3F2-E12-F10
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for TXNRD2 antibody: purified recombinant human TXNRD2 protein fragments expressed in E.coli.
Formulation	ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56 kDa
Gene Name	thioredoxin reductase 2
Database Link	NP_006431 Entrez Gene 10587 Human UniProt ID Q9NNW7
Background	Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22.
Synonyms	SELZ; TR; TR-BETA; TR3; TRXR2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Pyrimidine metabolism

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