KDM5B Rabbit Polyclonal Antibody
CNY 4,323.00
货期*
5周
规格
经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | ELISA (1:100 ?? 1:200) ; Western blotting (1:500) |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-Jarid1b antibody: mouse Jarid1b (Jumonji, AT rich interactive domain 1B), using a KLH-conjugated synthetic peptides containing an amino acid sequence from the central part of the protein. |
Concentration | lot specific |
Purification | Whole antiserum from rabbit containing 0.05% azide. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | lysine demethylase 5B |
Database Link | |
Background | JARID1B (UniProt/Swiss-Prot entry Q9UGL1) is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor. |
Synonyms | CT31; JARID1B; PLU-1; PLU1; PPP1R98; PUT1; RBBP2H1A |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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