Dysferlin (DYSF) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Dysferlin Antibody: A synthesized peptide derived from human Dysferlin
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	240 kDa
Gene Name	dysferlin
Database Link	NP_001123927 Entrez Gene 26903 MouseEntrez Gene 8291 Human UniProt ID O75923
Background	DYSF Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Belongs to the ferlin family. Interacts with CACNA1S. Interacts with ANXA1; the interaction is Ca(2+)- and injury state-dependent.
Synonyms	FER1L1; LGMD2B; MMD1
Note	Dysferlin antibody detects endogenous levels of total Dysferlin
Reference Data
Protein Families	Transmembrane

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