Metabotropic Glutamate Receptor 8 (GRM8) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-mGluR8 Antibody: A synthesized peptide derived from human mGluR8
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	100 kDa
Gene Name	glutamate metabotropic receptor 8
Database Link	NP_000836 Entrez Gene 14823 MouseEntrez Gene 60590 RatEntrez Gene 2918 Human UniProt ID O00222
Background	mGluR8 Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. Belongs to the G-protein coupled receptor 3 family. Interacts with PICK1. 3 isoforms of the human protein are produced by alternative splicing
Synonyms	GLUR8; GPRC1H; mGlu8; MGLUR8
Note	mGluR8 antibody detects endogenous levels of total mGluR8
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

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