SCN1A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Sodium Channel-pan Antibody: A synthesized peptide derived from human Sodium Channel-pan
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	230 kDa
Gene Name	sodium voltage-gated channel alpha subunit 1
Database Link	NP_001159435 Entrez Gene 20265 MouseEntrez Gene 81574 RatEntrez Gene 6323 Human UniProt ID P35498
Background	SCN5A This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform.
Synonyms	EIEE6; FEB3; FEB3A; FHM3; GEFSP2; HBSCI; NAC1; Nav1.1; SCN1; SMEI
Note	Sodium Channel-pan antibody detects endogenous levels of total Sodium Channel-pan
Reference Data
Protein Families	Druggable Genome, Transmembrane

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