GRP94 (HSP90B1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-GRP94 Antibody: A synthesized peptide derived from human GRP94
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	92 kDa
Gene Name	heat shock protein 90kDa beta family member 1
Database Link	NP_003290 Entrez Gene 22027 MouseEntrez Gene 7184 Human UniProt ID P14625
Background	GRP94 Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Homodimer; disulfide-linked. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5.
Synonyms	ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1
Note	GRP94 Antibody detects endogenous levels of GRP94
Reference Data
Protein Families	Druggable Genome
Protein Pathways	NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer

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