RNF14 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-RNF14 Antibody: A synthesized peptide derived from human RNF14
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50 kDa
Gene Name	ring finger protein 14
Database Link	NP_899647 Entrez Gene 56736 MouseEntrez Gene 619577 RatEntrez Gene 9604 Human UniProt ID Q9UBS8
Background	RNF14 Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription. Belongs to the RBR family. RNF14 subfamily. Interacts with the ubiquitin-conjugating enzymes UBE2E1 and UBE2E2 and in the presence of testosterone, with the androgen receptor (AR).
Synonyms	ARA54; HFB30; HRIHFB2038; TRIAD2
Note	RNF14 Antibody detects endogenous levels of RNF14
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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