FLT4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:1000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-VEGFR3 Antibody: Peptide sequence around aa.1279~1283 (L-A-S-E-E) derived from Human VEGFR-3.
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	160kd
Gene Name	fms related tyrosine kinase 4
Database Link	NP_891555 Entrez Gene 14257 MouseEntrez Gene 2324 Human UniProt ID P35916
Background	Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC
Synonyms	FLT-4; FLT41; LMPH1A; PCL; VEGFR-3; VEGFR3
Note	The antibody detects endogenous level of total VEGFR-3 protein.
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Focal adhesion

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