Angiopoietin 2 (ANGPT2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-ANG 2 Antibody: A synthesized peptide derived from human ANG 2
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	57 kDa
Gene Name	angiopoietin 2
Database Link	NP_001138 Entrez Gene 11601 MouseEntrez Gene 89805 RatEntrez Gene 285 Human UniProt ID O15123
Background	Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression.
Synonyms	AGPT2; ANG2
Note	ANG 2 Antibody detects endogenous levels of total ANG 2
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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