APC Rabbit Polyclonal Antibody
CAT#: TA348446
Rabbit Polyclonal Anti-Phospho-APC(Ser2054) Antibody
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
CNY 4,840.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 1:500-1:2000 |
Reactivity | Human |
Modifications | Phospho-specific |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-Phospho-APC(Ser2054) Antibody: A synthesized peptide derived from human APC around the phosphorylation site of Sersine 2054 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt |
Concentration | lot specific |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 311 kDa |
Gene Name | adenomatous polyposis coli |
Database Link | |
Background | This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
Synonyms | BTPS2; DP2; DP2.5; DP3; GS; PPP1R46 |
Note | Phospho-APC(Ser2054) Antibody detects endogenous levels of APC only when phosphorylated at Sersine 2054 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Pathways in cancer, Regulation of actin cytoskeleton, Wnt signaling pathway |
Documents
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Resources
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