Nucleophosmin (NPM1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Phospho-NPM (Thr199) Antibody: A synthesized peptide derived from human NPM around the phosphorylation site of Threonine 199
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	32 38 kDa
Gene Name	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Database Link	NP_954654 Entrez Gene 18148 MouseEntrez Gene 25498 RatEntrez Gene 4869 Human UniProt ID P06748
Background	a nucleolar protein associated with nucleolar ribonucleoprotein structures and that binds single-stranded nucleic acids. Is a major component of template activating factor (TAF)-III. It plays a role in controlling centrosome duplication, and may function in the assembly and/or transport of the ribosome. Two alternatively spliced isoforms have been described.
Synonyms	B23; NPM
Note	Phospho-NPM (Thr199) Antibody detects endogenous levels of NPM only when phosphorylated at Threonine 199
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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