AMHR2 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1-3 ug/ml
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	The immunogen for Anti-AMHR2 Antibody: Peptide with sequence HPQESHPFPESCPR, from the internal region of the protein sequence according to NP_065434.1; NP_001158163.1.
Formulation	Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	anti-Mullerian hormone receptor type 2
Database Link	NP_065434 Entrez Gene 269 Human UniProt ID Q16671
Background	This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]
Synonyms	AMHR; MISR2; MISRII; MRII
Note	This antibody is expected to recognize isoform 1 (NP_065434.1) and isoform 3 (NP_001158163.1).
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, TGF-beta signaling pathway

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