Fibrinogen gamma chain (FGG) Goat Polyclonal Antibody

CAT#: TA348963

Goat Polyclonal Anti-fibrinogen gamma chain (aa166-178) Antibody



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CNY 5,371.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 0.01-0.03 ug/ml
Reactivity Human
Host Goat
Clonality Polyclonal
Immunogen The immunogen for Anti-fibrinogen gamma chain (aa166-178) Antibody: Peptide with sequence C-KDTVQIHDITGKD, from the internal region of the protein sequence according to NP_000500.2; NP_068656.2.
Formulation Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name fibrinogen gamma chain
Background The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide
Note This antibody is expected to recognize both reported isoforms (NP_000500.2; NP_068656.2).
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Complement and coagulation cascades
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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