robld3 (LAMTOR2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	LAMTOR2 antibody was raised against an 18 amino acid peptide near the center of human LAMTOR2.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	LAMTOR2 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 14 kDa; Observed: 16 kDa
Gene Name	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Database Link	NP_054736 Entrez Gene 28956 Human UniProt ID Q9Y2Q5
Background	The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).
Synonyms	ANG-5; ANGPT5; ANL3; FHBL2
Reference Data

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