alpha Synuclein (SNCA) Rabbit Polyclonal Antibody

CAT#: TA349077

Rabbit Polyclonal Anti-SNCA Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen SNCA antibody was raised against a 19 amino acid peptide near the carboxy terminus of human SNCA.
Formulation PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification SNCA antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Condition Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Predicted Protein Size Predicted: 12 kDa; Observed: 16 kDa
Gene Name synuclein alpha
Background Alpha-Synuclein (SNCA) is a hallmark of Alzheimer?? disease (1,2). It is a cytoplasmic protein that is predominantly expressed in the central nervous system (2). SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to the decreased caspase-3 activation. SNCA may be involved in the regulation of dopamine release and transport and induces fibrillization of microtubule-associated protein tau (3). Defects in SNCA are associated with familial Parkinson?? disease (4,5).
Synonyms BAF190; BAF190A; BRG1; CSS4; hSNF2b; MRD16; RTPS2; SNF2; SNF2L4; SNF2LB; SWI2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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